Panacea Vacation Rentals

Compare Vacation Rentals & Rent By Owner Homes in Panacea, Florida, USA

Waterfront on Ochlockonee Bay-Renovated condo & sparking pool
10.0 (141 Reviews)
2 Bedrooms 4 Guests
Breezy Home w/Grills, Pool & Beach Access!
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10.0 (2 Reviews)
3 Bedrooms 8 Guests
The Panacea Motel
FromCA $217 per night
9.0 (146 Reviews)
1 Bedroom 2 Guests
Florida Abode - Private Beach Access & Ocean Views
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10.0 (2 Reviews)
3 Bedrooms 6 Guests
Hideaway Beach Cottage on waterfront with amazing views.
10.0 (68 Reviews)
2 Bedrooms 6 Guests
Nature Lover's Paradise: Hike, Bike & Fish!
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10.0 (2 Reviews)
3 Bedrooms 8 Guests
Alligator Point Beachfront Home w/Private Hot Tub
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10.0 (1 Review)
3 Bedrooms 7 Guests
Amazing Ochlockonee Riverfront Home!
10.0 (34 Reviews)
2 Bedrooms 9 Guests
romantic getaway bayside
FromCA $241 per night
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9.7 (27 Reviews)
1 Bedroom 2 Guests
Panacea Treehouse⭐️ Waterfront Spring Getaway-Boat Friendly!
10.0 (21 Reviews)
2 Bedrooms 6 Guests
Fun Beach House With Pool Alligator Point
9.7 (4 Reviews)
4 Bedrooms 11 Guests
SALT AIR AND SERENDIPITYn Unit B
FromCA $125 per night
10.0 (13 Reviews)
1 Bedroom 2 Guests
Waterfront Home: Spectacular On-Site Fishing!
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9.0 (2 Reviews)
3 Bedrooms 10 Guests
Tiny Tides Waterfront Cottage
FromCA $387 per night
10.0 (8 Reviews)
2 Bedrooms 6 Guests
Waterfront Ochlockonee Bay Cottage w/Views!
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8.4 (6 Reviews)
2 Bedrooms 8 Guests
Flip Flop- Flip to the pool or Flop to the beach!
10.0 (4 Reviews)
1 Bedroom 4 Guests
2 Mi to Mashes Sands Beach: Quiet Home w/Dock!
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8.0 (2 Reviews)
3 Bedrooms 6 Guests
Sea La Vie-Brand New Dock Home on the Bay
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New
3 Bedrooms 7 Guests
Coastal Cottage- a nature lover's paradise!
10.0 (1 Review)
2 Bedrooms 4 Guests
Ochlocknee Oasis- Unit A4
FromCA $231 per night
10.0 (1 Review)
1 Bedroom 4 Guests
Sardegna- pooldock home by Mashes Sands Beach!
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New
3 Bedrooms 8 Guests
Bayside Bungalow- Unit A8
FromCA $223 per night
10.0 (1 Review)
1 Bedroom 4 Guests
Mañana- a boaters bungalow
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New
3 Bedrooms 6 Guests
The Professor's Fish House- on the bay
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New
3 Bedrooms 8 Guests
Nirvana Beach House with Sauna & Hottub
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New
3 Bedrooms 7 Guests
Classic A-Frame By The Beach
FromCA $277 per night
9.8 (19 Reviews)
2 Bedrooms 4 Guests
For the Birds- on the water
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New
3 Bedrooms 5 Guests
Cozy bayfront farmhouse!
FromCA $321 per night
9.8 (6 Reviews)
2 Bedrooms 4 Guests
Coastal Getaway on canal-steps to the beach
9.6 (64 Reviews)
2 Bedrooms 8 Guests
Relax & Refresh: Waterfront Cottage in Panacea
9.6 (19 Reviews)
2 Bedrooms 5 Guests
Waterfront Ochlockonee Bay Cottage w/Views!
9.4 (29 Reviews)
2 Bedrooms 8 Guests
Cozy Panacea Retreat #3 (King)
FromCA $243 per night
9.0 (2 Reviews)
1 Bedroom 2 Guests
The Professor's Fish House- dock on the bay
10.0 (2 Reviews)
3 Bedrooms 8 Guests
Ochlockonee Bay 4 bedrooms, waterfront, pool, dock, fishing.
10.0 (1 Review)
4 Bedrooms 8 Guests
Bill's Bay Breeze
FromCA $321 per night
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New
2 Bedrooms 8 Guests
Shoreline Serenity- The Golden Goat on the Bay
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New
2 Bedrooms 4 Guests
Relax & Refresh: Waterfront Cottage in Panacea
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New
2 Bedrooms 5 Guests
Gated Water View Pool Home on Dickerson Bay
9.8 (12 Reviews)
4 Bedrooms 10 Guests
Waterfront Panacea Vacation Rental w/Dock!
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New
3 Bedrooms 8 Guests
Pachs Crab Shack
FromCA $337 per night
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New
1 Bedroom 6 Guests
Waterfront Panacea Vacation Rental w/Dock!
9.6 (11 Reviews)
3 Bedrooms 8 Guests
Fisherman's Retreat by BlueWater Realty Group
New
2 Bedrooms 6 Guests
Waterfront Home: Spectacular On-Site Fishing!
9.4 (26 Reviews)
3 Bedrooms 10 Guests
The Panacea Motel
FromCA $190 per night
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8.4 (90 Reviews)
92 Bedrooms 50 Guests
Sardegna- pool/dock home by Mashes Sands Beach!
9.4 (20 Reviews)
3 Bedrooms 8 Guests
2 Mi to Mashes Sands Beach: Quiet Home w/Dock!
9.4 (8 Reviews)
3 Bedrooms 6 Guests
Blue Zone – Your no-stress zone for sun-soaked fun
9.4 (6 Reviews)
3 Bedrooms 6 Guests
Relax with the whole family at this peaceful place to stay.
8.6 (8 Reviews)
4 Bedrooms 11 Guests
Secluded Florida Beach Bungalow MAY SALE 20% OFF!
10.0 (248 Reviews)
2 Bedrooms 6 Guests

About Panacea Vacation Rentals

With more than 324 Panacea vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Rent By Owner Homes (RBOs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an RBO property in Panacea.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With RentByOwner Panacea, you have the flexibility of comparing different options of various deals with a single click. Looking for an RBO with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (RBOs), and other popular Airbnb-style properties in Panacea. Places to stay near Panacea are 1113.66 ft² on average, with prices averaging CA $476 a night.

RentByOwner makes it easy and safe to find and compare vacation rentals in Panacea with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Frequently Asked Questions About Panacea?

What are the top vacation rentals in Panacea?

How many Rentbyowner vacation rentals are available in Panacea?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 324 in the Panacea area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Panacea.